RAJATA SINDOORA- EXPERIMENTAL STUDY ON SPERMATOGENIC ACTIVITY

Yousuf Sahad

Abstract


RajataSindoora (RS), a unique formulation mentioned in the various texts of Rasashastra is a KupipakwaRasayana(prepared using amber glass bottles). RS was prepared here as per the guidelines of the text RasendraSambhava with 4:4:1 proportions of ShodhitaParada(Purified Mercury), ShodhitaGandhaka(Purified Sulphur) and ShodhitaRajata(Purified Silver) respectively using modified method of Vertical Muffle Furnace. The author of the text Vaidya VishwanathDwivedi mentions that RS has rejuvenative, tissue boosting ,aphrodisiac, nootropic, beautifying properties and also possesses the potency to cure all the diseases on giving with appropriate anupanas(vehicles). RajataSindoora is widely claimed to have excellent vajikarana(spermatogenic) effect. Till date, no reported studies are available pertaining to spermatogenic effect of RS. Hence an attempt has been made to evaluate spermatogenic activity of RS experimentally on wistar strain male Albino rats and compared to Standard Fertisure-M underallnecessaryprecautions.RSwastaken in two different doses (250 mg/kgbw& 500 mg/kgbwt) and compared with Control (distilled water & food), Induced(Oligospermic rats) and Standard (Tab Fertisure-M)groups.Studyshowsincreaseinsperm count (up to 95-99 million) which shows effect of RS on spermatogenesis. It showed statistically significant Spermatogenic activity compared to control group & standard group. Histopathological study also showed increase in size of seminiferous tubules suggestive of significant Spermatogenicactivity.


Keywords


RajataSindoora, Kupipakwa, Tab Fertisure-M, Spermatogenic activity

References


PanditVishwanathaDwivedi ‘Vaidya’, RasendraSambhava, Varanasi, Krishnadas Academy, 1997, verse 26-28,481pp

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