A conceptual review of granulation technology in Ayurvedic pharmaceutics

  • Shilpa S N Dr Shilpa S N. MD (Ayu), Senior Consultant, Sriranga Ayurveda Chikitsa Mandira, Prakruthi Ayurveda Prathishtana®, Mysore.
  • Dayanand R D Research coordinator, Prakruthi Ayurveda Prathishtana ® Mysore.
  • Prasanna Venkatesh T S Chief Physician, Sriranga Ayurveda Chikitsa Mandira, Prakruthi Ayurveda Prathishtana®, Mysore.
Keywords: Granulation, shelf life, modification, modern technology

Abstract

In  today’s  era  of  globalisation  and  large  scale  production  of  Ayurvedic  formulations,  there  is  an  increasing  need  to  enhance  the  shelf  life  of  certain  dosage  forms.  Shelf  life  can  be  enhanced  by  modifying  the  dosage  forms  by  adopting  modern  technologies. Granulation  is  one  such  modern  technology  through  which  many  dosage  forms  like  swarasakwathachurnaavaleha  etc  can  be  modified.  Apart  from  increasing  the  shelf  life,  granule  form  of  the  medicament  is  having  added  benefits  like  rendering  palatability  to  the  drug,  improving  product  appearance,  convenience  in  handling,  dispensing,  and  storage.  It  even  improves  dissolution  of  the  drug,  thus  assuring  maximum  absorption  and  bio-availability.  But  while  adopting  these  modern  technologies  utmost  concern  should  be  taken  so  that  desired  therapeutic  efficacy  of  the  drug  is  not  compromised. This  paper  will  shed  light  upon  the  details  of  various  granulation  techniques,  their  merits  and  de-merits  when  adopted  to  Ayurvedic  formulations.

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Published
2018-11-15